Manufacturer: Merck Sharp
Pharmaceutical name: Finasteride
Pack: 28 tabs (5 mg/tab)
Proscar - contains and is made by , Germany.
In terms of the use of for steroid users, it would be related to the easing of several androgenic side effects often associated with the use of some anabolic and androgenic steroids. Of course due to the originally intended medical purpose of the drug steroid users suffering from prostate conditions due to their anabolic steroid use could be well served to use a drug such as Proscar. This will likely ease some of the discomfort caused by the activity of the DHT in the prostate tissue and related conditions. Similarly the androgenic activity of DHT in the scalp leading to hair loss can also prevented in some males with the use of a reductase inhibitor like . If the hair loss experienced by the user is related to an increase in the concentration and/or level of DHT in the tissue the administration of finasteride can help to reduce or prevent the severity of this side effect. A third side effect that the drug may help with is oily skin and/or acne. This androgenic side effect may be prevented or at the very least reduced in severity with the administration of Finasteride. However, anecdotally the results of this have been mixed to say the least and relatively few users administer the drug for this purpose.
For many these actions of will seem very similar to that of another reductase inhibitor, namely dutasteride. However these drugs do have differences. The major difference between them is that dutasteride targets both Type I and Type II 5-alpha reductase. Finasteride only targets Type II. Type I is more heavily concentrated in the liver and skin while Type II is found most prevalently in male reproductive organs. By targeting both types of the enzyme, dutasteride is better capable of reducing more DHT then Finasteride and is therefore thought to be more efficient and effective by most. Despite this, it is still not as popular as Finasteride but this is likely due to dutasteride having been on the market for a much shorter time as well as not currently being approved medically for use as a preventative measure against male pattern baldness.
Proscar has also been used as a so-called “masking agent” by some steroid users who are tested either via urine or blood. While the mechanism by which this is accomplished will not be discussed in this profile, it should however be noted that most organizations now recognize this fact and will test for along with anabolic steroids. For this reason users of finasteride who may be tested for such substances should be aware of this fact beforehand.
In terms of dosing for the , while tipical application of Proscar can yield results, most physicians will recommend and most users will choose to administer the drug orally. This is due to the greater rate of bioavailability compared to topical application. The bioavailability of Finasteride, when taken orally, ranges in the area of sixty-five percent of a one milligram tablet in clinical studies. It should also be noted that the bioavailability of was not affected when taken with or without food or liquids. Maximum suppression of DHT conversion occurs within twenty-four hours of administering a one milligram dose orally. This maximum suppression is approximately sixty-five of the total DHT conversion.
As for the size of dosage required, it depends on the reaction of the user. Most males that are prescribed as part of a medical treatment are most often given doses of one milligram per day. This may be more then necessary however. Anecdotally some users have indicated that doses of 5 mg/day or one milligram every other day have had the desired effect for some users. However other users may require larger doses to reap the benefits of the compound. For the most part these doses range from 1.5 milligrams per day to as high as 5 mg/day or higher. When increasing one’s dosage however a user should make these increases gradually so as to gage their response to the compound and avoid a dramatic onset of negative side effects.
is still a relatively new drug on the market and long-term studies on it continue to be done. However there are no indications that users have to limit themselves in regard to the duration of their use of the drug. It was designed to be administered for long periods of time and is seemingly well tolerated by the majority of users. For this reason steroid users should feel free to use Proscar for extended periods of time if they feel it necessary. The only limiting factors being any side effects that arise for the individual taking the compound or else the cost of the drug itself, or of course the fact that it is no longer required. Also, when discontinuing the use of there appears no need for a tapering of the drug to prevent a major rebound in DHT levels of the user. While obviously these levels will return to their normal concentrations no dramatic rise should be seen by the user.
For the most part the side effects associated with the use of Proscar are relatively minor and will not jeopardize the general health of the user. It appears that all of the reported side effects are related to its action as a reductase inhibitor and the lack of dihydrotestosterone (DHT) circulating in the system of the user when using this drug. Toxicity is not a concern as even with extremely large doses run for long durations no adverse reactions are observed.
The most common side effect reported with the administration of Proscar is seemingly sexual dysfunction and/or a reduction in sex drive. This is due to DHT playing a significant role in sex drive with it also being found in high concentrations in male sex organs playing a role in their proper function. To a lesser extent some users report that their strength is reduced when using and this can also be directly related to the drop in DHT present in the user. Similarly this may also result in a small reduction in muscle mass depending on the amount inhibited and the individual body chemistry of the user.